XERF™ and DermaV™ Combination Therapy for Firmer Skin

Today’s aesthetic patients often have more than one concern. Some want to address skin laxity while reducing redness, while others may experience a less defined facial contour, uneven skin tone, and dark spots that make the face look tired. Therefore, planning treatment with only one type of technology may not address every aspect of the skin.

Combination Therapy, or the integration of multiple technologies within a single treatment plan, has become increasingly important for comprehensive skin care. This is especially true for XERF™ and DermaV™, which have clearly differentiated roles. XERF™ focuses on skin tightening and deeper skin structures, while DermaV™ targets concerns related to redness, vascular lesions, and pigmentation.

When the treatment sequence and energy settings are planned appropriately, physicians can create programs that address facial contours, skin elasticity, and evenness of skin tone while giving clinics more options to offer increasingly personalized treatment programs.

 

What Is XERF™ and What Role Does It Play in Skin Structure?

XERF™ is a Monopolar Radiofrequency (RF) technology that uses monopolar radiofrequency energy to deliver heat into tissue at depths selected by the physician. It is designed to address skin laxity and stimulate collagen remodeling. The technology operates at frequencies of 6.78 MHz and 2 MHz, allowing physicians to plan treatment according to the depth and characteristics of the targeted area.

The primary role of XERF™ is to focus on skin firmness, elasticity, facial contours, and facial dimensions rather than directly treating pigmentation concerns. It also features Real Time Impedance Feedback, which monitors skin impedance during energy delivery and helps physicians maintain greater control throughout the treatment.

Clinics looking to expand their skin tightening services can explore information about the XERF™ device to determine whether it is suitable for their service model and patient base.

 

What Is DermaV™ and How Does It Address Skin Tone Concerns?

DermaV™ is a dual-wavelength laser that operates at 532 nm and 1064 nm. It is designed to give physicians greater versatility when targeting vascular and pigmentation concerns.

The 532 nm wavelength is suitable for relatively superficial targets, such as redness, small blood vessels, and certain types of pigmentation. The 1064 nm wavelength penetrates deeper, providing greater flexibility when planning treatments for concerns located at different depths.

While XERF™ focuses on skin structure, DermaV™ is used to refine visible skin concerns, including uneven skin tone, redness, dark spots, and an overall dull appearance.

DermaV™ also features a Cryogen Cooling system to help reduce heat at the surface of the skin and improve patient comfort during treatment. However, physicians must still select the appropriate wavelength, spot size, pulse duration, and energy settings according to each patient’s skin tone and lesion characteristics.

Clinics considering expanding their pigmentation and vascular treatment services can review information about purchasing a DermaV™ laser to support investment planning and treatment menu development.

 

Why Do XERF™ and DermaV™ Work Well Together?

The key principle of Combination Therapy is selecting technologies that address different targets while complementing the overall treatment outcome. Using two devices with similar functions may unnecessarily increase heat or irritation. In contrast, combining technologies that work at different skin depths can help physicians address concerns more systematically.

XERF™ focuses on firmness, elasticity, and tissue structure, while DermaV™ focuses on vascular irregularities, pigmentation, and skin tone. Patients experiencing both skin laxity and redness therefore do not need to choose only one concern to address. Physicians can design a plan that covers both facial contours and skin quality while adjusting the emphasis of each technology according to the patient’s primary concern. For example, XERF™ may be prioritized for patients with more noticeable laxity, while DermaV™ may play a greater role for those primarily concerned with redness and uneven skin tone.

 

How Should XERF™ and DermaV™ Techniques Be Planned?

When using two technologies together, each patient may require different energy settings or numbers of shots. XERF™ and DermaV™ techniques should begin with a thorough skin assessment and an appropriate treatment sequence, as follows.

 

Assess the Skin and Primary Concerns Before Treatment

Physicians should evaluate the degree of skin laxity, skin thickness, amount of subcutaneous fat, redness, vascular concerns, pigmentation, and previous aesthetic procedures. Contraindications and conditions that may require treatment to be postponed should also be assessed.

Prioritizing concerns also helps determine the appropriate proportion of each treatment. For example, a patient with significant redness but only mild laxity may not require the same RF energy level as someone with poorly defined facial contours.

 

Plan the Sequence From Deeper Structures to the Skin Surface

In many cases, physicians may begin with XERF™ to address deeper tissue before using DermaV™ to target redness, vascular concerns, or pigmentation at the skin surface. One reason is that XERF™ relies on impedance readings, so the skin should ideally remain in its normal condition without swelling or cooling caused by a previous laser procedure.

However, this sequence is not a fixed formula for every patient. Physicians may separate treatments into different days, reduce energy settings, or modify the treatment steps if the patient has sensitive skin, localized lesions, or requires relatively high energy levels.

 

Adjust Energy Settings in Relation to Each Other

When physicians use two devices on the same day, they should consider the cumulative effect of energy. Each device should not be set as though it were being used as a standalone treatment without considering the other procedure.

Areas with thinner skin, such as around the eyes, forehead, or jawline, may respond differently from the cheeks. Physicians therefore need to adjust energy levels, number of pulses, and number of passes for each area while monitoring the skin’s response throughout the procedure.

 

Plan the Treatment Course Based on Skin Response

Results from collagen stimulation take time to develop, while vascular or pigmentation concerns may require more than one treatment. The number of sessions and intervals between sessions should therefore be based on each patient’s response rather than using a fixed package without reassessment during the course.

 

Who Is the Combination of XERF™ and DermaV™ Suitable For?

A combination of XERF™ and DermaV™ may be suitable for patients with multiple skin concerns who want to address both facial structure and overall skin quality within one treatment plan. However, physicians should evaluate skin condition, degree of laxity, vascular and pigmentation characteristics, and medical history before planning treatment.

 

Patients With Skin Laxity Along With Redness or Visible Blood Vessels

Patients who begin to notice reduced firmness, less defined facial contours, or laxity together with redness and visible capillaries may be suitable candidates for XERF™ and DermaV™ techniques, as the two technologies address different targets.

XERF™ focuses on deeper skin structures and skin elasticity, while DermaV™ uses selected wavelengths to target vascular concerns and redness. Combining the two technologies can therefore support a firmer overall facial appearance together with a more even skin tone, without relying on a single device to address every concern.

 

Patients With Melasma, Freckles, Dark Spots, and Uneven Skin Texture

Some patients experience more than pigmentation concerns. Their skin may also lack firmness, appear uneven in texture, or give the face a tired appearance. DermaV™ alone may be used to address melasma, freckles, or dark spots based on physician assessment, but it is not designed to correct skin laxity.

Adding XERF™ to the plan allows physicians to address firmness and skin structure at the same time, while DermaV™ focuses on pigmentation irregularities and skin tone. This approach may therefore suit patients seeking broader skin rejuvenation rather than treatment of one isolated concern.

 

Patients Who Want to Address Multiple Concerns Within Limited Time

Patients with busy schedules or limited availability for multiple clinic visits may be interested in programs that combine skin tightening with skin tone treatments during the same appointment. In many cases, XERF™ and DermaV™ can be performed consecutively on the same day if the physician considers that the skin is suitable.

This approach can reduce repetitive appointments and streamline the treatment plan, but it does not mean every patient will require fewer sessions. Collagen response, redness, vascular concerns, and pigmentation vary from person to person. Some patients may benefit more from treatments on separate days or a series of sessions to better manage the skin’s response.

 

Benefits of Combination Treatments for Clinics

The advantages of combining Laser and RF technologies come from selecting technologies with complementary roles while planning the treatment sequence and energy levels according to each patient’s concerns.

 

Address Both Skin Structure and Skin Tone in One Plan

One of the main advantages of XERF™ and DermaV™ techniques is their distinctive roles. XERF™ focuses on firmness, elasticity, and skin structure, while DermaV™ targets redness, vascular concerns, and pigmentation.

These two modalities allow physicians to plan treatments ranging from deeper skin layers to visible concerns at the surface. Patients do not necessarily have to choose whether to address facial contours or skin tone first if their skin condition allows both technologies to be combined.

 

Improve Treatment Planning and Patient Satisfaction

Patients with multiple concerns may feel that single-modality treatment does not fully address their overall goals. For example, skin may appear firmer while redness remains visible, or skin tone may become more even while facial contours still lack definition.

Combination planning allows physicians to address several treatment targets, helping patients better understand the direction of their treatment and how each step connects with the next. Therefore, patient satisfaction may come not only from the outcome itself, but also from the treatment experience and a plan tailored to individual needs.

However, program effectiveness depends on diagnosis, parameter selection, and follow–up. Using two devices should not automatically be assumed to produce better results without considering the skin’s limitations.

 

Adapt Treatment Plans to Skin Condition and Budget

Physicians can adjust the proportion of XERF™ and DermaV™ according to each patient’s primary concerns. For example, XERF™ machines may be emphasized for patients with more noticeable laxity, while DermaV™ laser may receive greater focus when redness and pigmentation are the main concerns.

This flexibility also extends to whether treatments are performed on the same day or on separate days, the number of sessions, and the intervals between sessions. Clinics can therefore design different program levels according to treatment goals, patient availability, and budget rather than offering the same package to everyone.

When discussing XERF™ and DermaV™ price considerations, clinics can also design programs according to the proportion of each technology used, the treatment area, number of sessions, and individualized treatment needs. This approach creates opportunities for clinics to develop differentiated programs for various patient groups while maintaining the essential principle that every treatment plan must remain medically appropriate and safe.

 

Build More Comprehensive Skin Programs With Technologies That Complement Each Other

Combining XERF™ and DermaV™ provides an approach that addresses skin from deeper structures through to visible skin tone concerns. The effectiveness of the plan depends on understanding how each technology works, evaluating each patient appropriately, and adjusting energy settings to suit individual needs.

For clinics looking to expand their skin rejuvenation capabilities, having technologies that address firmness, redness, vascular concerns, and pigmentation gives physicians greater flexibility in designing treatment programs. It can also support services that reflect treatment quality, patient experience, and practical business value.

AESTELLAR provides information on technology, service positioning, practical approaches to integrating devices into each clinic’s individual context, and comprehensive after-sales support. The goal is to help transform investment in aesthetic equipment into practical treatment capabilities while supporting sustainable business growth alongside long-term medical standards.

Fill out the form on our website to contact us today. For more information, contact LINE: @Aestellar or call 063-669-9699.

 

References:

1. Noninvasive radio frequency for skin tightening and body contouring. Retrieved on 31 July 2026 from https://pubmed.ncbi.nlm.nih.gov/24049924/.